Molecular analysis of two mouse dilute locus deletion mutations: spontaneous dilute lethal20J and radiation-induced dilute prenatal lethal Aa2 alleles
MC Strobel, PK Seperack, NG Copeland… - Molecular and …, 1990 - Am Soc Microbiol
… d alleles can now be accomplished. As illustrated in this study, this combined molecular and
genetic analysis … of the d locus but also of other loci in the d region of mouse chromosome 9. …
genetic analysis … of the d locus but also of other loci in the d region of mouse chromosome 9. …
The genetic risk in mice from radiation: an estimate of the mutation induction rate per genome
J Asakawa, M Kodaira, HM Cullings… - Radiation …, 2013 - meridian.allenpress.com
… 1 mice in the control group, which suggested a spontaneous … possible large deletions detected
in the specific locus tests. … 0.38) of radiation-induced alleles are lethal under homozygous …
in the specific locus tests. … 0.38) of radiation-induced alleles are lethal under homozygous …
A genome scanning approach to assess the genetic effects of radiation in mice and humans
J Asakawa, R Kuick, M Kodaira… - Radiation …, 2004 - meridian.allenpress.com
… estimates of spontaneous and radiation-induced mutation rates… deletion mutations is (0.17
± 0.09) × 10 −5 /locus Gy –1 . Assuming that 50% of radiation-induced mutations are deletions …
± 0.09) × 10 −5 /locus Gy –1 . Assuming that 50% of radiation-induced mutations are deletions …
Mutations affecting early development in the mouse
T Magnuson, SK Sharan, B Holdener-Kenny - Preimplantation Embryo …, 1993 - Springer
… the known mutations in mouse have occurred spontaneously … for radiation-induced,
noncontinuous, or skipping, mutations … of the shaker 1 locus and 2 mutations at a new locus called …
noncontinuous, or skipping, mutations … of the shaker 1 locus and 2 mutations at a new locus called …
Why genetic effects of radiation are observed in mice but not in humans
N Nakamura - Radiation Research, 2018 - meridian.allenpress.com
… specific loci; ie, they inherited one mutant allele from the … (malformation, stillbirth and
perinatal death). Subsequent studies … the mutation rates (both spontaneous and radiation-induced) …
perinatal death). Subsequent studies … the mutation rates (both spontaneous and radiation-induced) …
Molecular genetic dissection of mouse unconventional myosin-VA: head region mutations
… The mouse dilute (d) locus encodes unconventional myosin-… d xn alleles, some spontaneous
and radiation-induced alleles … Point mutations, deletions and insertions in the cDNA can be …
and radiation-induced alleles … Point mutations, deletions and insertions in the cDNA can be …
TERRY MAGNUSON, SHYAM K. SHARAN, AND BERNADETTE HOLDENER-KENNY
MA Early - Preimplantation Embryo Development, 1993 - books.google.com
… the known mutations in mouse have occurred spontaneously … for radiation-induced,
noncontinuous, or skipping, mutations … of the shaker 1 locus and 2 mutations at a new locus called …
noncontinuous, or skipping, mutations … of the shaker 1 locus and 2 mutations at a new locus called …
The mouse neurological mutant flailer expresses a novel hybrid gene derived by exon shuffling between Gnb5 and Myo5a
JM Jones, JD Huang, V Mermall… - Human Molecular …, 2000 - academic.oup.com
… for evolution of new genes. Here we show that the mouse neurological mutation flailer (flr)
expresses a novel gene that combines the promoter and first two exons of guanine nucleotide …
expresses a novel gene that combines the promoter and first two exons of guanine nucleotide …
Myosin V associates with melanosomes in mouse melanocytes: evidence that myosin V is an organelle motor
X Wu, B Bowers, Q Wei, B Kocher… - Journal of cell …, 1997 - journals.biologists.com
… Mice with mutations at the dilute locus exhibit a ‘washed out’ or ‘diluted’ coat color. The
pigments … In this study, we show by light immunofluorescence microscopy and immunoelectron …
pigments … In this study, we show by light immunofluorescence microscopy and immunoelectron …
The predominant defect in dilute melanocytes is in melanosome distribution and not cell shape, supporting a role for myosin V in melanosome transport
QIN Wei, X Wu, JA Hammer - Journal of Muscle Research & Cell Motility, 1997 - Springer
… Mice with mutations at the dilute locus, which encodes the … were homozygous for the dilute
lethal allele d120J. These latter … This allele, which contains a 3.2 Kb deletion within the dilute …
lethal allele d120J. These latter … This allele, which contains a 3.2 Kb deletion within the dilute …